A14696G-F1

**Figure 1\. Pedigree diagram for family A14696G\-F1\.**

![](/media/202606/20260626170454186064.png)

# Pedigree Information

| **No.** | **Position** | **Variant** | **Family ID** | **Nationality** | **Diseases** | **Unaffected Maternal Relatives** | **Affected Maternal Relatives** | **Publication Year** | **PMID/Ref** | **Note** |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1 | 14696 | m.14696A\>G | A14696G\-F1 | China | Hypertension | 3 | 2 | 2024 | [38222291](https://pubmed.ncbi.nlm.nih.gov/38222291/) |  |

The **m.14696A\>G** variant in MT\-TE was reported in family A14696G\-F1 from China with hypertension. The pedigree record reported 3 unaffected and 2 affected maternal relatives, and the carrier table includes 3 listed carriers. Homoplasmy was reported in all listed carriers; 3/3 carriers were affected, and the main clinical manifestation among affected carriers was hypertension.

# Carrier Information

| **No.** | **Position** | **Variant** | **Family ID** | **Carrier ID** | **Type (Fam/De novo/Uninf)** | **Gender (F/M)** | **Proband (Y/N)** | **Affected (Y/N)** | **Die/Alive(D/A)** | **Age** | **Blood Mutant Level** | **Muscle Mutant level** | **Urine Mutant level** | **Other Mutant level** | **Clinical Features** | **Note** |
| --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- |
| 1 | 14696 | m.14696A\>G | A14696G\-F1 | A14696G\-F1\-I2 | Uninf | F | N | Y | A | 88 | Homo | / | / | / | Hypertension |  |
| 2 | 14696 | m.14696A\>G | A14696G\-F1 | A14696G\-F1\-II6 | Fam | F | Y | Y | A | 66 | Homo | / | / | / | Hypertension |  |
| 3 | 14696 | m.14696A\>G | A14696G\-F1 | A14696G\-F1\-III4 | Fam | F | N | Y | A | 40 | Homo | / | / | / | Hypertension |  |

For abbreviations and other usage instructions, please see [Mitofam Info](https://mitofam.com/doc/385/).